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DNA Tandem Lesion Repair by Strand Displacement Synthesis and Nucleotide Excision Repair

DNA tandem lesions are comprised of two contiguously damaged nucleotides. This subset of clustered lesions is produced by a variety of oxidizing agents, including ionizing radiation. Clustered lesions can inhibit base excision repair (BER). We report the effects of tandem lesions composed of a thymi...

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Detalhes bibliográficos
Main Authors: Imoto, Shuhei, Bransfield, Leslie A., Croteau, Deborah L., Van Houten, Bennett, Greenberg, Marc M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2432464/
https://ncbi.nlm.nih.gov/pubmed/18341293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi7021427
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