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UBE2S drives elongation of K11-linked ubiquitin chains by the Anaphase-Promoting Complex
The Anaphase-Promoting Complex (APC) is an E3 ubiquitin ligase that regulates mitosis and G1 by sequentially targeting cell-cycle regulators for ubiquitination and proteasomal degradation. The mechanism of ubiquitin chain formation by APC and the resultant chain topology remains controversial. By us...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2802591/ https://ncbi.nlm.nih.gov/pubmed/20080579 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0912802107 |
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