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Nicotinamide Glycolates Antagonize CXCR2 Activity through an Intracellular Mechanism

The chemokine receptors CXCR1/2 are involved in a variety of inflammatory diseases, including chronic obstructive pulmonary disease. Several classes of allosteric small-molecule CXCR1/2 antagonists have been developed. The data presented here describe the cellular pharmacology of the acid and ester...

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Main Authors: Maeda, Dean Y., Quinn, Mark T., Schepetkin, Igor A., Kirpotina, Liliya N., Zebala, John A.
Formato: Artigo
Idioma:Inglês
Publicado: The American Society for Pharmacology and Experimental Therapeutics 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2802484/
https://ncbi.nlm.nih.gov/pubmed/19779130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.109.159020
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