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Transport of the Photodynamic Therapy Agent 5-Aminolevulinic Acid by Distinct H(+)-Coupled Nutrient Carriers Coexpressed in the Small Intestine
5-Aminolevulinic acid (ALA) is a prodrug used in photodynamic therapy, fluorescent diagnosis, and fluorescent-guided resection because it leads to accumulation of the photosensitizer protoporphyrin IX (PpIX) in tumor tissues. ALA has good oral bioavailability, but high oral doses are required to obt...
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| Autori principali: | , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The American Society for Pharmacology and Experimental Therapeutics
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2802479/ https://ncbi.nlm.nih.gov/pubmed/19789362 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.109.159822 |
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