Transport of the Photodynamic Therapy Agent 5-Aminolevulinic Acid by Distinct H(+)-Coupled Nutrient Carriers Coexpressed in the Small Intestine

5-Aminolevulinic acid (ALA) is a prodrug used in photodynamic therapy, fluorescent diagnosis, and fluorescent-guided resection because it leads to accumulation of the photosensitizer protoporphyrin IX (PpIX) in tumor tissues. ALA has good oral bioavailability, but high oral doses are required to obt...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Anderson, Catriona M. H., Jevons, Mark, Thangaraju, Muthusamy, Edwards, Noel, Conlon, Nichola J., Woods, Steven, Ganapathy, Vadivel, Thwaites, David T.
Format: Artigo
Langue:Inglês
Publié: The American Society for Pharmacology and Experimental Therapeutics 2010
Sujets:
Metabolism, Transport, and Pharmacogenomics
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2802479/
https://ncbi.nlm.nih.gov/pubmed/19789362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.109.159822
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires