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Probing Anomalous Structural Features in Polypurine Tract-Containing RNA–DNA Hybrids with Neomycin B
During (−)-strand DNA synthesis in retroviruses and Saccharomyces cerevisiae LTR retrotransposons, a purine rich region of the RNA template, known as the polypurine tract (PPT), is resistant to RNase H-mediated hydrolysis and subsequently serves as a primer for (+)-strand, DNA-dependent DNA synthesi...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2009
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2802280/ https://ncbi.nlm.nih.gov/pubmed/19449839 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi900357j |
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