Probing Anomalous Structural Features in Polypurine Tract-Containing RNA–DNA Hybrids with Neomycin B

During (−)-strand DNA synthesis in retroviruses and Saccharomyces cerevisiae LTR retrotransposons, a purine rich region of the RNA template, known as the polypurine tract (PPT), is resistant to RNase H-mediated hydrolysis and subsequently serves as a primer for (+)-strand, DNA-dependent DNA synthesi...

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Main Authors: Brinson, Robert G., Turner, Kevin B., Yi-Brunozzi, Hye Young, Le Grice, Stuart F. J., Fabris, Daniele, Marino, John P.
格式: Artigo
語言:Inglês
出版: 2009
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2802280/
https://ncbi.nlm.nih.gov/pubmed/19449839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi900357j
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