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The histone variant macroH2A1 marks repressed autosomal chromatin, but protects a subset of its target genes from silencing

MacroH2A1 is a histone variant that is enriched on the inactive X chromosome (Xi) in mammals and is postulated to play an important, but unknown, role in the repression of gene expression. Here we show that, although macroH2A1 marks repressed autosomal chromatin, it positively regulates transcriptio...

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Autors principals: Gamble, Matthew J., Frizzell, Kristine M., Yang, Christine, Krishnakumar, Raga, Kraus, W. Lee
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2802188/
https://ncbi.nlm.nih.gov/pubmed/20008927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1876110
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