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The histone variant macroH2A1 marks repressed autosomal chromatin, but protects a subset of its target genes from silencing
MacroH2A1 is a histone variant that is enriched on the inactive X chromosome (Xi) in mammals and is postulated to play an important, but unknown, role in the repression of gene expression. Here we show that, although macroH2A1 marks repressed autosomal chromatin, it positively regulates transcriptio...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Cold Spring Harbor Laboratory Press
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2802188/ https://ncbi.nlm.nih.gov/pubmed/20008927 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1876110 |
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