MacroH2A histone variants limit chromatin plasticity through two distinct mechanisms

MacroH2A histone variants suppress tumor progression and act as epigenetic barriers to induced pluripotency. How they impart their influence on chromatin plasticity is not well understood. Here, we analyze how the different domains of macroH2A proteins contribute to chromatin structure and dynamics....

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Detalhes bibliográficos
Publicado no:EMBO Rep
Main Authors: Kozlowski, Marek, Corujo, David, Hothorn, Michael, Guberovic, Iva, Mandemaker, Imke K, Blessing, Charlotte, Sporn, Judith, Gutierrez‐Triana, Arturo, Smith, Rebecca, Portmann, Thomas, Treier, Mathias, Scheffzek, Klaus, Huet, Sebastien, Timinszky, Gyula, Buschbeck, Marcus, Ladurner, Andreas G
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Scientific Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6172464/
https://ncbi.nlm.nih.gov/pubmed/30177554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201744445
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