MacroH2A histone variants limit chromatin plasticity through two distinct mechanisms

MacroH2A histone variants suppress tumor progression and act as epigenetic barriers to induced pluripotency. How they impart their influence on chromatin plasticity is not well understood. Here, we analyze how the different domains of macroH2A proteins contribute to chromatin structure and dynamics....

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Detalles Bibliográficos
Publicado en:EMBO Rep
Autores principales: Kozlowski, Marek, Corujo, David, Hothorn, Michael, Guberovic, Iva, Mandemaker, Imke K, Blessing, Charlotte, Sporn, Judith, Gutierrez‐Triana, Arturo, Smith, Rebecca, Portmann, Thomas, Treier, Mathias, Scheffzek, Klaus, Huet, Sebastien, Timinszky, Gyula, Buschbeck, Marcus, Ladurner, Andreas G
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2018
Materias:
Scientific Reports
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6172464/
https://ncbi.nlm.nih.gov/pubmed/30177554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201744445
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