DNA adducts of aristolochic acid II: total synthesis and site-specific mutagenesis studies in mammalian cells

Aristolochic acids I and II (AA-I, AA-II) are found in all Aristolochia species. Ingestion of these acids either in the form of herbal remedies or as contaminated wheat flour causes a dose-dependent chronic kidney failure characterized by renal tubulointerstitial fibrosis. In ∼50% of these cases, th...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Attaluri, Sivaprasad, Bonala, Radha R., Yang, In-Young, Lukin, Mark A., Wen, Yujing, Grollman, Arthur P., Moriya, Masaaki, Iden, Charles R., Johnson, Francis
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
Assuntos:
Synthetic Biology and Chemistry
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2800210/
https://ncbi.nlm.nih.gov/pubmed/19854934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp815
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados