Sulfotransferase-1A1-dependent bioactivation of aristolochic acid I and N-hydroxyaristolactam I in human cells

Aristolochic acids (AA) are implicated in the development of chronic renal disease and upper urinary tract carcinoma in humans. Using in vitro approaches, we demonstrated that N-hydroxyaristolactams, metabolites derived from partial nitroreduction of AA, require sulfotransferase (SULT)-catalyzed con...

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Bibliografski detalji
Izdano u:Carcinogenesis
Glavni autori: Hashimoto, Keiji, Zaitseva, Irina N., Bonala, Radha, Attaluri, Sivaprasad, Ozga, Katherine, Iden, Charles R., Johnson, Francis, Moriya, Masaaki, Grollman, Arthur P., Sidorenko, Viktoriya S.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2016
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Original Manuscript
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4936383/
https://ncbi.nlm.nih.gov/pubmed/27207664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgw045
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