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Energetic signatures of single base bulges: thermodynamic consequences and biological implications

DNA bulges are biologically consequential defects that can arise from template-primer misalignments during replication and pose challenges to the cellular DNA repair machinery. Calorimetric and spectroscopic characterizations of defect-containing duplexes reveal systematic patterns of sequence-conte...

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Detalhes bibliográficos
Main Authors: Minetti, Conceição A. S. A., Remeta, David P., Dickstein, Rian, Breslauer, Kenneth J.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2800203/
https://ncbi.nlm.nih.gov/pubmed/19946018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp1036
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