تحميل...
Impact of α-Hydroxy-Propanodeoxyguanine Adducts on DNA Duplex Energetics: Opposite Base Modulation and Implications for Mutagenicity and Genotoxicity
Acrolein is an α,β-unsaturated aldehyde that is a major environmental pollutant, as well as a product of cellular metabolism. DNA bases react with acrolein to form two regioisomeric exocyclic guanine adducts, namely γ-hydroxy-propanodeoxyguanosine (γ-OH-PdG) and its positional isomer α-hydroxy-propa...
محفوظ في:
| المؤلفون الرئيسيون: | , , , , |
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| التنسيق: | Artigo |
| اللغة: | Inglês |
| منشور في: |
2010
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| الموضوعات: | |
| الوصول للمادة أونلاين: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2891022/ https://ncbi.nlm.nih.gov/pubmed/19937758 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bip.21355 |
| الوسوم: |
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