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Human POT1 is required for efficient telomere C-rich strand replication in the absence of WRN
Mechanisms of telomere replication remain poorly defined. It has been suggested that G-rich telomeric strand replication by lagging mechanisms requires, in a stochastic way, the WRN protein. Here we show that this requirement is more systematic than previously thought. Our data are compatible with a...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Cold Spring Harbor Laboratory Press
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2800086/ https://ncbi.nlm.nih.gov/pubmed/20008939 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.544009 |
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