RPA prevents G-rich structure formation at lagging-strand telomeres to allow maintenance of chromosome ends

Replication protein A (RPA) is a highly conserved heterotrimeric single-stranded DNA-binding protein involved in DNA replication, recombination, and repair. In fission yeast, the Rpa1-D223Y mutation provokes telomere shortening. Here, we show that this mutation impairs lagging-strand telomere replic...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:EMBO J
Main Authors: Audry, Julien, Maestroni, Laetitia, Delagoutte, Emmanuelle, Gauthier, Tiphaine, Nakamura, Toru M, Gachet, Yannick, Saintomé, Carole, Géli, Vincent, Coulon, Stéphane
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley & Sons, Ltd 2015
Assuntos:
Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4547897/
https://ncbi.nlm.nih.gov/pubmed/26041456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201490773
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares