Human POT1 is required for efficient telomere C-rich strand replication in the absence of WRN

Mechanisms of telomere replication remain poorly defined. It has been suggested that G-rich telomeric strand replication by lagging mechanisms requires, in a stochastic way, the WRN protein. Here we show that this requirement is more systematic than previously thought. Our data are compatible with a...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Arnoult, Nausica, Saintome, Carole, Ourliac-Garnier, Isabelle, Riou, Jean-François, Londoño-Vallejo, Arturo
Materialtyp: Artigo
Språk:Inglês
Publicerad: Cold Spring Harbor Laboratory Press 2009
Ämnen:
Research Paper
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2800086/
https://ncbi.nlm.nih.gov/pubmed/20008939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.544009
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk