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Neuronal SIRT1 regulates endocrine and behavioral responses to calorie restriction
Mammalian life span can be extended by both calorie restriction (CR) and mutations that diminish somatotropic signaling. Sirt1 is a mediator of many effects of CR in mammals, but any role in controlling somatotropic signaling has not been shown. Since the somatotropic axis is controlled by the brain...
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| 主要な著者: | , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Cold Spring Harbor Laboratory Press
2009
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2800085/ https://ncbi.nlm.nih.gov/pubmed/20008932 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1839209 |
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