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Expression of mutant huntingtin in mouse brain astrocytes causes age-dependent neurological symptoms
Huntington disease (HD) is an inherited neurological disorder caused by a polyglutamine expansion in the protein huntingtin and is characterized by selective neurodegeneration that preferentially occurs in striatal medium spiny neurons. Because the medium spiny neurons are innervated abundantly by g...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2799722/ https://ncbi.nlm.nih.gov/pubmed/20018729 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0911503106 |
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