Expression of mutant huntingtin in glial cells contributes to neuronal excitotoxicity

Huntington disease (HD) is characterized by the preferential loss of striatal medium-sized spiny neurons (MSNs) in the brain. Because MSNs receive abundant glutamatergic input, their vulnerability to excitotoxicity may be largely influenced by the capacity of glial cells to remove extracellular glut...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Shin, Ji-Yeon, Fang, Zhi-Hui, Yu, Zhao-Xue, Wang, Chuan-En, Li, Shi-Hua, Li, Xiao-Jiang
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 2005
Schlagworte:
Research Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2171327/
https://ncbi.nlm.nih.gov/pubmed/16365166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200508072
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge