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Expression of mutant huntingtin in glial cells contributes to neuronal excitotoxicity
Huntington disease (HD) is characterized by the preferential loss of striatal medium-sized spiny neurons (MSNs) in the brain. Because MSNs receive abundant glutamatergic input, their vulnerability to excitotoxicity may be largely influenced by the capacity of glial cells to remove extracellular glut...
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| Autores principales: | , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
The Rockefeller University Press
2005
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2171327/ https://ncbi.nlm.nih.gov/pubmed/16365166 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200508072 |
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