Identification of known and novel pancreas genes expressed downstream of Nkx2.2 during development

BACKGROUND: The homeodomain containing transcription factor Nkx2.2 is essential for the differentiation of pancreatic endocrine cells. Deletion of Nkx2.2 in mice leads to misspecification of islet cell types; insulin-expressing β cells and glucagon-expressing α cells are replaced by ghrelin-expressi...

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Hlavní autoři: Anderson, Keith R, White, Peter, Kaestner, Klaus H, Sussel, Lori
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2009
Témata:
Research article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2799404/
https://ncbi.nlm.nih.gov/pubmed/20003319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-213X-9-65
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