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Nkx2.2:Cre Knock-In Mouse Line: A Novel Tool for Pancreas- and CNS-Specific Gene Deletion
Nkx2.2 is a homeodomain-containing transcriptional regulator necessary for the appropriate differentiation of ventral neuronal populations in the spinal cord and hindbrain, and endocrine cell populations in the pancreas and intestine. In each tissue, Nkx2.2 inactivation leads to reciprocal cell fate...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2013
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3902634/ https://ncbi.nlm.nih.gov/pubmed/23996959 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvg.22715 |
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