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Novel computational analysis of protein binding array data identifies direct targets of Nkx2.2 in the pancreas

BACKGROUND: The creation of a complete genome-wide map of transcription factor binding sites is essential for understanding gene regulatory networks in vivo. However, current prediction methods generally rely on statistical models that imperfectly model transcription factor binding. Generation of ne...

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Main Authors: Hill, Jonathon T, Anderson, Keith R, Mastracci, Teresa L, Kaestner, Klaus H, Sussel, Lori
格式: Artigo
語言:Inglês
出版: BioMed Central 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3050729/
https://ncbi.nlm.nih.gov/pubmed/21352540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-12-62
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