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Novel computational analysis of protein binding array data identifies direct targets of Nkx2.2 in the pancreas

BACKGROUND: The creation of a complete genome-wide map of transcription factor binding sites is essential for understanding gene regulatory networks in vivo. However, current prediction methods generally rely on statistical models that imperfectly model transcription factor binding. Generation of ne...

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Hlavní autoři: Hill, Jonathon T, Anderson, Keith R, Mastracci, Teresa L, Kaestner, Klaus H, Sussel, Lori
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3050729/
https://ncbi.nlm.nih.gov/pubmed/21352540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-12-62
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