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Identification of known and novel pancreas genes expressed downstream of Nkx2.2 during development
BACKGROUND: The homeodomain containing transcription factor Nkx2.2 is essential for the differentiation of pancreatic endocrine cells. Deletion of Nkx2.2 in mice leads to misspecification of islet cell types; insulin-expressing β cells and glucagon-expressing α cells are replaced by ghrelin-expressi...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2799404/ https://ncbi.nlm.nih.gov/pubmed/20003319 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-213X-9-65 |
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