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Nkx2.2 Activates the Ghrelin Promoter in Pancreatic Islet Cells
Nkx2.2 is an essential regulator of pancreatic endocrine differentiation. Nkx2.2-null mice are completely devoid of β-ells and have a large reduction of α- and PP cells. In the place of these islet populations, there is a corresponding increase in the ghrelin-positive ε-cells. Molecular studies have...
Gorde:
| Egile Nagusiak: | , , , , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
The Endocrine Society
2010
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2817598/ https://ncbi.nlm.nih.gov/pubmed/19965928 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2009-0360 |
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