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Nkx2.2 Activates the Ghrelin Promoter in Pancreatic Islet Cells
Nkx2.2 is an essential regulator of pancreatic endocrine differentiation. Nkx2.2-null mice are completely devoid of β-ells and have a large reduction of α- and PP cells. In the place of these islet populations, there is a corresponding increase in the ghrelin-positive ε-cells. Molecular studies have...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Endocrine Society
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2817598/ https://ncbi.nlm.nih.gov/pubmed/19965928 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2009-0360 |
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