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Nkx2.2:Cre Knock-In Mouse Line: A Novel Tool for Pancreas- and CNS-Specific Gene Deletion

Nkx2.2 is a homeodomain-containing transcriptional regulator necessary for the appropriate differentiation of ventral neuronal populations in the spinal cord and hindbrain, and endocrine cell populations in the pancreas and intestine. In each tissue, Nkx2.2 inactivation leads to reciprocal cell fate...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Balderes, Dina A., Magnuson, Mark A., Sussel, Lori
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3902634/
https://ncbi.nlm.nih.gov/pubmed/23996959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvg.22715
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