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Pharmacologic inhibition of fatty acid oxidation sensitizes human leukemia cells to apoptosis induction
The traditional view is that cancer cells predominately produce ATP by glycolysis, rather than by oxidation of energy-providing substrates. Mitochondrial uncoupling — the continuing reduction of oxygen without ATP synthesis — has recently been shown in leukemia cells to circumvent the ability of oxy...
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| 主要な著者: | , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Clinical Investigation
2009
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2799198/ https://ncbi.nlm.nih.gov/pubmed/20038799 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI38942 |
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