Sensitization of ABCB1 Overexpressing Cells to Chemotherapeutic Agents by FG020326 via Binding to ABCB1 and Inhibiting Its Function

The effectiveness of chemotherapeutic treatment is usually limited by the overexpression of adenosine triphosphate binding cassette (ABC) transporters, which mediate multidrug resistance (MDR) by acting as efflux pumps to remove chemotherapeutic agents from MDR cancer cells. Thus, the inhibition of...

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Détails bibliographiques
Auteurs principaux: Dai, Chun-ling, Liang, Yong-ju, Chen, Li-ming, Zhang, Xu, Deng, Wen-jing, Su, Xiao-dong, Shi, Zhi, Wu, Chung-pu, Ashby, Charles R., Akiyama, Shin-ichi, Ambudkar, Suresh V., Chen, Zhe-sheng, Fu, Li-wu
Format: Artigo
Langue:Inglês
Publié: 2009
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2798597/
https://ncbi.nlm.nih.gov/pubmed/19410561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2009.04.023
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