The Open Reading Frame 3a Protein of Severe Acute Respiratory Syndrome-Associated Coronavirus Promotes Membrane Rearrangement and Cell Death

The genome of the severe acute respiratory syndrome-associated coronavirus (SARS-CoV) contains eight open reading frames (ORFs) that encode novel proteins. These accessory proteins are dispensable for in vitro and in vivo replication and thus may be important for other aspects of virus-host interact...

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Main Authors: Freundt, Eric C., Yu, Li, Goldsmith, Cynthia S., Welsh, Sarah, Cheng, Aaron, Yount, Boyd, Liu, Wei, Frieman, Matthew B., Buchholz, Ursula J., Screaton, Gavin R., Lippincott-Schwartz, Jennifer, Zaki, Sherif R., Xu, Xiao-Ning, Baric, Ralph S., Subbarao, Kanta, Lenardo, Michael J.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 2010
Teme:
Virus-Cell Interactions
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2798367/
https://ncbi.nlm.nih.gov/pubmed/19889773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01662-09
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