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Severe Acute Respiratory Syndrome Coronavirus Open Reading Frame (ORF) 3b, ORF 6, and Nucleocapsid Proteins Function as Interferon Antagonists

The severe acute respiratory syndrome coronavirus (SARS-CoV) is highly pathogenic in humans, with a death rate near 10%. This high pathogenicity suggests that SARS-CoV has developed mechanisms to overcome the host innate immune response. It has now been determined that SARS-CoV open reading frame (O...

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Detalhes bibliográficos
Main Authors: Kopecky-Bromberg, Sarah A., Martínez-Sobrido, Luis, Frieman, Matthew, Baric, Ralph A., Palese, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1797484/
https://ncbi.nlm.nih.gov/pubmed/17108024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01782-06
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