The Open Reading Frame 3a Protein of Severe Acute Respiratory Syndrome-Associated Coronavirus Promotes Membrane Rearrangement and Cell Death

The genome of the severe acute respiratory syndrome-associated coronavirus (SARS-CoV) contains eight open reading frames (ORFs) that encode novel proteins. These accessory proteins are dispensable for in vitro and in vivo replication and thus may be important for other aspects of virus-host interact...

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Hauptverfasser: Freundt, Eric C., Yu, Li, Goldsmith, Cynthia S., Welsh, Sarah, Cheng, Aaron, Yount, Boyd, Liu, Wei, Frieman, Matthew B., Buchholz, Ursula J., Screaton, Gavin R., Lippincott-Schwartz, Jennifer, Zaki, Sherif R., Xu, Xiao-Ning, Baric, Ralph S., Subbarao, Kanta, Lenardo, Michael J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2010
Schlagworte:
Virus-Cell Interactions
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2798367/
https://ncbi.nlm.nih.gov/pubmed/19889773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01662-09
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