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Functional Cooperation of the Proapoptotic Bcl2 Family Proteins Bmf and Bim In Vivo
Bcl2-modifying factor (Bmf) is a member of the BH3-only group of proapoptotic proteins. To test the role of Bmf in vivo, we constructed mice with a series of mutated Bmf alleles that disrupt Bmf expression, prevent Bmf phosphorylation by the c-Jun NH(2)-terminal kinase (JNK) on Ser(74), or mimic Bmf...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Microbiology (ASM)
2010
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2798311/ https://ncbi.nlm.nih.gov/pubmed/19841067 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01155-09 |
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