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Multi-site Phosphorylation Regulates Bim Stability and Apoptotic Activity
The pro-apoptotic BH3-only protein Bim is established to be an important mediator of signaling pathways that induce cell death. Multi-site phosphorylation of Bim by several members of the MAP kinase group is implicated as a regulatory mechanism that controls the apoptotic activity of Bim. To test th...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2008
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2453504/ https://ncbi.nlm.nih.gov/pubmed/18498746 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2008.03.025 |
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