Looping out and deletion mechanism for the immunoglobulin heavy-chain class switch.
In the mouse pre-B-cell line 18-81, cells can switch production in vitro from immunoglobulin mu chain to gamma 2b chain. The gene encoding the gamma 2b chain is created by a rearrangement of the mu gene. This rearrangement always takes place within a homolog. In cells with a gamma 2b gene, most of t...
Spremljeno u:
| Izdano u: | Proc Natl Acad Sci U S A |
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| Glavni autori: | , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
National Academy of Sciences
1988
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC279817/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2830623/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.5.1581 |
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