Immunoglobulin heavy chain genes: demethylation accompanies class switching.
The methylation of immunoglobulin heavy chain genes was examined before and after class switching, by using the Hpa II/Msp I restriction mapping technique. The mu, delta, and gamma 1 genes all are methylated in cells that do not express them but are demethylated when they are expressed. In particula...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1981
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC349295/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6801653/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.78.12.7497 |
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