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Immunoglobulin heavy chain genes: demethylation accompanies class switching.

The methylation of immunoglobulin heavy chain genes was examined before and after class switching, by using the Hpa II/Msp I restriction mapping technique. The mu, delta, and gamma 1 genes all are methylated in cells that do not express them but are demethylated when they are expressed. In particula...

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Detalles Bibliográficos
Autores principales: Rogers, J, Wall, R
Formato: Artigo
Lenguaje:Inglês
Publicado: 1981
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC349295/
https://ncbi.nlm.nih.gov/pubmed/6801653
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