Looping out and deletion mechanism for the immunoglobulin heavy-chain class switch.

In the mouse pre-B-cell line 18-81, cells can switch production in vitro from immunoglobulin mu chain to gamma 2b chain. The gene encoding the gamma 2b chain is created by a rearrangement of the mu gene. This rearrangement always takes place within a homolog. In cells with a gamma 2b gene, most of t...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Jäck, H M, McDowell, M, Steinberg, C M, Wabl, M
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1988
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC279817/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2830623/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.5.1581
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