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Looping out and deletion mechanism for the immunoglobulin heavy-chain class switch.

In the mouse pre-B-cell line 18-81, cells can switch production in vitro from immunoglobulin mu chain to gamma 2b chain. The gene encoding the gamma 2b chain is created by a rearrangement of the mu gene. This rearrangement always takes place within a homolog. In cells with a gamma 2b gene, most of t...

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Detalles Bibliográficos
Main Authors: Jäck, H M, McDowell, M, Steinberg, C M, Wabl, M
Formato: Artigo
Idioma:Inglês
Publicado: 1988
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC279817/
https://ncbi.nlm.nih.gov/pubmed/2830623
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