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ATP-Sensitive K(+) Channel Mediates the Zinc Switch-Off Signal for Glucagon Response During Glucose Deprivation
OBJECTIVE: The intraislet insulin hypothesis proposes that glucagon secretion during hypoglycemia is triggered by a decrease in intraislet insulin secretion. A more recent hypothesis based on in vivo data from hypoglycemic rats is that it is the decrease in zinc cosecreted with insulin from β-cells,...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
American Diabetes Association
2010
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2797913/ https://ncbi.nlm.nih.gov/pubmed/19808893 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db09-1098 |
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