Pancreatic Islet β-cell and Oxidative Stress: the Importance of Glutathione Peroxidase

Por Robertson, R. Paul, Harmon, Jamie S.
Publicado em 2007

A role for glutathione peroxidase in protecting pancreatic β cells against oxidative stress in a model of glucose toxicity

Por Tanaka, Yoshito, Tran, Phuong Oanh T., Harmon, Jamie, Robertson, R. Paul
Publicado em 2002

ATP-Sensitive K(+) Channel Mediates the Zinc Switch-Off Signal for Glucagon Response During Glucose Deprivation

Por Slucca, Michela, Harmon, Jamie S., Oseid, Elizabeth A., Bryan, Joseph, Robertson, R. Paul
Publicado em 2010

Prevention of glucose toxicity in HIT-T15 cells and Zucker diabetic fatty rats by antioxidants

Por Tanaka, Yoshito, Gleason, Catherine E., Tran, Phuong Oanh T., Harmon, Jamie S., Robertson, R. Paul
Publicado em 1999

Regulation of the Insulin Gene by Glucose and Fatty Acids

Por Poitout, Vincent, Hagman, Derek, Stein, Roland, Artner, Isabella, Robertson, R. Paul, Harmon, Jamie S.
Publicado em 2006

Lipotoxicity of the Pancreatic β-Cell Is Associated With Glucose-Dependent Esterification of Fatty Acids Into Neutral Lipids

Por Briaud, Isabelle, Harmon, Jamie S., Kelpe, Cynthia L., Segu, Venkatesh Babu G., Poitout, Vincent
Publicado em 2001

Cyclooxygenase-2, Not Microsomal Prostaglandin E Synthase-1, Is the Mechanism for Interleukin-1β-induced Prostaglandin E(2) Production and Inhibition of Insulin Secretion in Pancre...

Por Parazzoli, Susan, Harmon, Jamie S., Vallerie, Sara N., Zhang, Tao, Zhou, Huarong, Robertson, R. Paul
Publicado em 2012

The B55α-containing PP2A holoenzyme dephosphorylates FOXO1 in islet β-cells under oxidative stress

Por Yan, Ling, Guo, Shuangli, Brault, Marie, Harmon, Jamie, Robertson, R. Paul, Hamid, Rizwan, Stein, Roland, Yang, Elizabeth
Publicado no Biochem J (2012)

Inactivation of specific β cell transcription factors in type 2 diabetes

Por Guo, Shuangli, Dai, Chunhua, Guo, Min, Taylor, Brandon, Harmon, Jamie S., Sander, Maike, Robertson, R. Paul, Powers, Alvin C., Stein, Roland
Publicado em 2013

β-Cell-Specific Overexpression of Glutathione Peroxidase Preserves Intranuclear MafA and Reverses Diabetes in db/db Mice

Por Harmon, Jamie S., Bogdani, Marika, Parazzoli, Susan D., Mak, Sabrina S. M., Oseid, Elizabeth A., Berghmans, Marleen, LeBoeuf, Renée C., Robertson, R. Paul
Publicado em 2009

Ebselen Treatment Prevents Islet Apoptosis, Maintains Intranuclear Pdx-1 and MafA Levels, and Preserves β-Cell Mass and Function in ZDF Rats

Por Mahadevan, Jana, Parazzoli, Susan, Oseid, Elizabeth, Hertzel, Ann V., Bernlohr, David A., Vallerie, Sara N., Liu, Chang-qin, Lopez, Melissa, Harmon, Jamie S., Robertson, R. Paul
Publicado em 2013