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A role for glutathione peroxidase in protecting pancreatic β cells against oxidative stress in a model of glucose toxicity

Antioxidant drugs have been reported to protect pancreatic islets from the adverse effects of chronic exposure to supraphysiological glucose concentrations. However, glucose has not been shown to increase intracellular oxidant load in islets, nor have the effects of increasing or inhibiting glutathi...

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Hlavní autoři: Tanaka, Yoshito, Tran, Phuong Oanh T., Harmon, Jamie, Robertson, R. Paul
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2002
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC129450/
https://ncbi.nlm.nih.gov/pubmed/12218186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.192445199
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