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Regulation of the Insulin Gene by Glucose and Fatty Acids

The insulin gene is expressed almost exclusively in pancreatic β-cells. Metabolic regulation of insulin gene expression enables the β-cell to maintain adequate stores of intracellular insulin to sustain the secretory demand. Glucose is the major physiologic regulator of insulin gene expression; it c...

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Detalhes bibliográficos
Main Authors: Poitout, Vincent, Hagman, Derek, Stein, Roland, Artner, Isabella, Robertson, R. Paul, Harmon, Jamie S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1853259/
https://ncbi.nlm.nih.gov/pubmed/16549443
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