Role of K(ATP) Channels in Glucose-Regulated Glucagon Secretion and Impaired Counterregulation in Type 2 Diabetes

Glucagon, secreted by pancreatic islet α cells, is the principal hyperglycemic hormone. In diabetes, glucagon secretion is not suppressed at high glucose, exacerbating the consequences of insufficient insulin secretion, and is inadequate at low glucose, potentially leading to fatal hypoglycemia. The...

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Detaylı Bibliyografya
Asıl Yazarlar: Zhang, Quan, Ramracheya, Reshma, Lahmann, Carolina, Tarasov, Andrei, Bengtsson, Martin, Braha, Orit, Braun, Matthias, Brereton, Melissa, Collins, Stephan, Galvanovskis, Juris, Gonzalez, Alejandro, Groschner, Lukas N., Rorsman, Nils J.G., Salehi, Albert, Travers, Mary E., Walker, Jonathan N., Gloyn, Anna L., Gribble, Fiona, Johnson, Paul R.V., Reimann, Frank, Ashcroft, Frances M., Rorsman, Patrik
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Cell Press 2013
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Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3851686/
https://ncbi.nlm.nih.gov/pubmed/24315372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2013.10.014
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