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Reinterpreting the Action of ATP Analogs on K(ATP) Channels

Neuroendocrine-type K(ATP) channels, (SUR1/Kir6.2)(4), couple the transmembrane flux of K(+), and thus membrane potential, with cellular metabolism in various cell types including insulin-secreting β-cells. Mutant channels with reduced activity are a cause of congenital hyperinsulinism, whereas hype...

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Detalhes bibliográficos
Main Authors: Ortiz, David, Gossack, Lindsay, Quast, Ulrich, Bryan, Joseph
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3696665/
https://ncbi.nlm.nih.gov/pubmed/23665564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.476887
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