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Intracranial Administration of P Gene siRNA Protects Mice from Lethal Chandipura Virus Encephalitis

BACKGROUND: In parts of India, Chandipura Virus (CHPV) has emerged as an encephalitis causing pathogen in both epidemic and sporadic forms. This pediatric disease follows rapid course leading to 55–75% mortality. In the absence of specific treatment, effectiveness of RNA interference (RNAi) was eval...

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Hlavní autoři: Kumar, Satyendra, Arankalle, Vidya A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2797643/
https://ncbi.nlm.nih.gov/pubmed/20062542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0008615
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