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Structural Elements for the Generation of Sustained Currents by the Acid Pain Sensor ASIC3
ASIC3 is an acid-sensing ion channel expressed in sensory neurons, where it participates in acidic and inflammatory pain. In addition to the “classical” transient current, ASIC3 generates a sustained current essential for pain perception. Using chimeras between the ASIC3 and ASIC1a channels we show...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Biochemistry and Molecular Biology
2009
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2797256/ https://ncbi.nlm.nih.gov/pubmed/19778905 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.043984 |
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