Global Analysis of Transcriptional Regulation by Poly(ADP-ribose) Polymerase-1 and Poly(ADP-ribose) Glycohydrolase in MCF-7 Human Breast Cancer Cells

Poly(ADP-ribose) polymerase-1 (PARP-1) and poly(ADP-ribose) glycohydrolase (PARG) are enzymes that modify target proteins by the addition and removal, respectively, of ADP-ribose polymers. Although a role for PARP-1 in gene regulation has been well established, the role of PARG is less clear. To inv...

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Bibliografiske detaljer
Main Authors: Frizzell, Kristine M., Gamble, Matthew J., Berrocal, Jhoanna G., Zhang, Tong, Krishnakumar, Raga, Cen, Yana, Sauve, Anthony A., Kraus, W. Lee
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2009
Fag:
Transcription, Chromatin, and Epigenetics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2797163/
https://ncbi.nlm.nih.gov/pubmed/19812418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.023879
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