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Differential Association of Phosphodiesterase 4D Isoforms with β(2)-Adrenoceptor in Cardiac Myocytes
cAMP and protein kinase A (PKA) activation represents a key signaling mechanism upon β-adrenergic stimulation under stress. Both β(1)- and β(2)-adrenoreceptor (ARs) subtypes induce cAMP accumulation, yet play distinct roles in cardiac contraction and myocyte apoptosis. Differences in controlling cAM...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2009
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2797152/ https://ncbi.nlm.nih.gov/pubmed/19801680 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.020388 |
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