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The 26 S Proteasome: From Basic Mechanisms to Drug Targeting
The regulated degradation of proteins within eukaryotes and bacterial cells is catalyzed primarily by large multimeric proteases in ATP-dependent manner. In eukaryotes, the 26 S proteasome is essential for the rapid destruction of key regulatory proteins, such as cell cycle regulators and transcript...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2797140/ https://ncbi.nlm.nih.gov/pubmed/19812037 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.R109.018481 |
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