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The life cycle of the 26S proteasome: from birth, through regulation and function, and onto its death
The 26S proteasome is a large, ∼2.5 MDa, multi-catalytic ATP-dependent protease complex that serves as the degrading arm of the ubiquitin system, which is the major pathway for regulated degradation of cytosolic, nuclear and membrane proteins in all eukaryotic organisms.
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| Publicat a: | Cell Res |
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| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4973335/ https://ncbi.nlm.nih.gov/pubmed/27444871 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2016.86 |
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